1. Медицина / Medicine
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Changes in Glial Populations in the Human Telencephalon Following Ischemic Injury // Промени в глиални популации на човешки теленцефалон след исхемична увреда
(Medical University of Varna, 2024)A significant amount of evidence has been accumulated regarding the ability of glial cells to exert both inflammatory and anti-inflammatory effects in various pathological conditions. In combination with their proliferation ... -
Pharmacological Investigation with Anethole in an Experimental Model of Obesity // Фармакологични проучвания с анетол в експериментален модел на затлъстяване
(Medical University of Varna, 2024)The thesis aims to investigate and summarise the pharmacological activity of monoterpene anethole administered orally in increasing doses to rats in a model of obesity induced by a high-calorie diet. For this purpose, 50 ... -
Changes in Water-Electrolyte Balance in Organ Donors with Brain Death and Their Correction in the Intensive Care Unit // Промени във водно-електролитното равновесие при органен донор с мозъчна смърт и корекцията им в интензивната клиника
(Medical University of Varna, 2024)Brain death is a condition of complete and irreversible cessation of all functions of the brain and brainstem while maintaining circulation in the rest of the body. In approximately 80% of organ donors with brain death, ... -
Assessment of Oxidative Stress and Early Vascular Damage in Children and Young Adults with Beta-Thalassemia Major // Оценка на оксидативния стрес и ранната съдова увреда при деца и млади възрастни с бета-таласемия майор
(Medical University of Varna, 2024)Patients with beta-thalassemia major (BTM) are exposed to significant oxidative stress due to iron overload. Free radicals oxidise various cellular components, leading to the formation of end compounds such as malondialdehyde ... -
Analysis of Molecular Genetic Markers in Patients with Acute Myelogenous Leukemia // Изследване на молекулярно-генетични маркери при пациенти с остра миелогенна левкемия
(Medical University of Varna, 2024)Acute myelogenous leukaemia (AML) occurs due to the abnormal proliferation of progenitor cells of the myeloid lineage. At the cellular level, it is an underlying genetic disorder associated with genetic and epigenetic ... -
Quality of Life and Comorbidity in Children with Epilepsy // Качество на живот и коморбидност при деца с епилепсия
(Medical University of Varna, 2024)Epilepsy is a chronic disease of the central nervous system, combining various conditions and syndromes, with particular importance in childhood. Some of the affected patients have comorbidities. The concept of "health-related ... -
Application of Videofluoroscopy for Evaluation of the Neohypopharynx In Patients Following Laryngectomy // Приложение на видеофлуороскопията за оценка на неохипофаринкса при пациенти след ларингектомия
(Medical University of Varna, 2024)The research aimed to evaluate the possibilities and role of videofluoroscopy in the early and late postoperative period, as well as for the follow-up of patients following laryngectomy. To achieve this goal, a standardised ... -
Biomarkers for Assessing Bone Disease in Multiple Myeloma // Биомаркери за оценка на костната болест при мултиплен миелом
(Medical University of Varna, 2024)Multiple myeloma (MM) is an oncohematological disease with increasing incidence in recent years. A characteristic manifestation of MM is bone disease (BD), with 80% of patients having proven osteolytic lesions at diagnosis. ... -
Organisation and Results of a Programme for Early Detection and Follow-Up of Children Born Small for Their Gestational Age // Организация и резултати от програма за ранно откриване и обхващане на деца, родени малки за гестационната си възраст
(Medical University of Varna, 2024)The thesis explores the issue of children born small for their gestational age (SGA). The thesis aims to create, introduce and evaluate a scientifically applied approach (Programme) to define and track the SGA children in ... -
The diagnostic role of 18F-FDG PET/CT in multiple myeloma // Диагностичната роля на 18F-FDG PET/CT при мултиплен миелом
(Medical University of Varna, 2024)The advantages and effectiveness of the PET/CT hybrid imaging method with radiopharmaceutical 18F-FDG in multiple myeloma were analysed and systematised within the framework of the thesis. We used various statistical methods ... -
Genotype-Phenotype Correlation in Patients with Cystic Fibrosis // Генотип-фенотип корелация при пациенти с кистозна фиброза
(Medical University of Varna, 2024)Genotype-Phenotype Correlation in Patients with Cystic Fibrosis // Генотип-фенотип корелация при пациенти с кистозна фиброза Genotype-phenotype correlations in patients with cystic fibrosis have been interesting since the ... -
Antiviral Therapy in Chronic Hepatitis B – Viral Marker Dynamics and Long-Term Outcomes // Антивирусна терапия при хроничен хепатит В – динамика на вирусните маркери и дългосрочни резултати
(Medical University of Varna, 2024)The thesis presents an in-depth assessment of the effectiveness of antiviral treatment for hepatitis B virus (HBV). 84 patients with chronic hepatitis B or liver cirrhosis on long-term nucleoside/nucleotide treatment from ... -
Research on the Participation of Humoral Factors of Congenital Immunity in the Pathogenesis of Activated Osteoarthritis // Изследване участието на хуморалните фактори на вродения имунитет в патогенезата на активираната остеоартроза
(Medical University of Varna, 2024)The thesis examines the role of humoral factors of innate immunity in the pathogenesis of activated osteoarthritis (OA) of the knee joint. Data from numerous studies indicate that the question of whether the complement ... -
Pharmacological Evaluation of the Effects of Chaenomeles Maulei Fruit Juice in an Experimental Model of Metabolic Syndrome // Фармакологично проучване на ефектите на плодов сок от Chaenomeles maulei в експериментален модел на метаболитен синдром
(Medical University of Varna, 2024)The thesis examines the pharmacological effects of Chaenomeles maulei fruit juice in an experimental model of metabolic syndrome. For the purposes of the experiment, for 10 weeks, 50 male Wistar rats, divided into 5 groups ... -
Analysis of Microglia during the Prenatal Development of the Human Telencephalon // Анализ на микроглия по време на пренаталното развитие на краен мозък при човек
(Medical University of Varna, 2024)The present study aimed to investigate the amount and distribution of microglial cells in the germinative zones of the human dorsal telencephalon during the peak period of neurogenesis and to examine the correlation between ... -
Localisation and Characteristics of Progenitor Cells during the Prenatal Development of Teeth in Humans // Локализация и характеристика на прогениторни клетки по време на пренаталното развитие на зъб при човек
(Medical University of Varna, 2024)Progenitor cells in the dental pulp have been poorly studied, and the interest in them has been progressively increasing over the last two decades due to the wide therapeutic and regenerative potential that they present. ... -
Expression of Tumour Reversion Markers in Colorectal Cancer // Експресия на маркери за туморна реверсия при колоректален карцином
(Medical University of Varna, 2024)The thesis research focuses on identifying TCTP as a new prognostic biomarker in patients with histologically verified colorectal carcinoma. The retrospective study included 74 participants who received antitumour treatment ... -
Modelling and 3D Printing of Morphologically Correct Bone Matrix // Моделиране и 3D принтиране на морфологично достоверна костна матрица
(Medical University of Varna, 2023)The thesis focuses on 3D printing methods used for constructing models representing three main aspects of bone tissue: Macroscopic: Represents the bone as a macroscopic organ and explores methods for creating a model ... -
Intraabdominal Abscesses // Интраабдоминални абсцеси
(Medical University of Varna, 2023)Intraabdominal abscesses are a significant cause of morbidity and mortality. They are common surgical emergencies and have been reported as a major contributor to non-traumatic deaths in emergency departments worldwide. ... -
Postcholecystectomy Syndrome – an Update of an "Old" Problem. Diagnosis and Modern Therapeutic Strategy // Постхолецистектомичен синдром - актуален поглед върху “стар“ проблем. Диагностика и съвременна терапевтична стратегия
(Medical University of Varna, 2023)Since the 1990s, laparoscopic cholecystectomy has replaced open cholecystectomy, and its frequency has increased, probably due to its relatively timely performance. Despite the large number of cholecystectomies performed ...
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