Катедра по фармакология и клинична фармакология и терапия / Department of Pharmacology, Clinical Pharmacology and Therapeutics
Recent Submissions
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Pharmacological Study of the Behavioral Effects of Biologically Active Substances of Plant Origin in Experimental Animal Models of Depression // Фармакологично проучване на поведенчески ефекти на биологично активни вещества от растителен произход в модели на депресия при опитни животни
(Medical University of Varna, 2022)The thesis studies the effects of Aronia melanocarpa fruit juice and the phenolic acids – chlorogenic, ferulic and gallic in experimental models of behavioural disorders in rats induced by ovariectomy and olfactory bulbectomy. ... -
Pharmacological Investigation of the Effects of Aronia Melanocarpa Fruit Juice in an Experimental Model of Metabolic Syndrome // Фармакологично проучване на ефектите на плодов сок от Aronia melanocarpa в експериментален модел на метаболитен синдром
(Medical University of Varna, 2022)This thesis aims to study and summarize the pharmacological effects of Aronia melanocarpa fruit juice in rats with diet-induced metabolic syndrome. For this objective, male Wistar rats were fed a high-fat, high-fructose ... -
Novel RGD/polyamines – Synthesis and Study of Antitumor Activity // Нови RGD/полиамини – синтез и проучване на противотуморна активност
(Medical University of Varna, 2022)Malignant neoplasms are one of the leading causes of death and significant public health problems. Along with hypertension and cardiovascular disease, cancer is defined as one of the riskiest in Bulgaria. One of the main ... -
Pharmacological Study of The Behavioural Effects of Chaenomeles Maulei in Experimental Animals // Фармакологично проучване на поведенчески ефекти на Chaenomeles maulei при експериментални животни
(Medical University of Varna, 2020)According to a World Health Organization report, psychiatric disorders affect more than 264 million people worldwide and are a leading cause of disability for people of all ages. Depression is one of the most common ... -
Pharmacological Study of the Effects of Biologically Active Substances of Plant Origin in an Experimental Model of Inflammatory Bowel Disease // Фармакологично проучване на ефектите на биологично активни вещества от растителен произход в експериментален модел на възпалителни чревни заболявания
(Medical University of Varna, 2020)Inflammatory bowel disease (IBD) is a group of diseases with diverse clinical manifestations, which are united by the presence of chronic intestinal inflammation and are divided into two main nosological units: Crohn’s ... -
Identification, Analysis and Evaluation of Pharmacokinetic and Pharmacodynamics Drug Interaction // Идентификация, анализ и оценка на фармакокинетични и фармакодинамични лекарствени взаимодействия
(Medical University of Varna, 2020)The identification, analysis, and evaluation of drug interactions are crucial in the preclinical phase of the development and implementation of new drugs. All new drug molecules, substrates, inhibitors, or inducers of ... -
Pharmacotherapeutic Study, Potential Side and Toxic Effects of Cardioactive Drugs in the Treatment of Hospitalized Patients with Chronic Heart Failure /// Фармакотерапевтично проучване, потенциални странични и токсични ефекти на кардиоактивни медикаменти при лечение на хоспитализирани пациенти с хронична сърдечна недостатъчност
(2018)The thesis presents a systemization and summary of the demographic data and pharmacological therapy of 535 hospitalized patients with a diagnosis of chronic decompensated heart failure, with preserved (HFpEF) and reduced ... -
Effects of Vitamin K in an Experimental Model of Metabolic Syndrome /// Ефекти на витамин К при експериментален модел на метаболитен синдром
(2018)Vitamin K is required for the carboxylation of many proteins in the liver and outside liver. The subclinical vitamin K deficiency impairs its extrahepatic functions and is linked to the development of age-related diseases, ... -
Psychopharmacological Effects of Phenolic Acids in Experimental Pharmacological Studies // Психофармакологични ефекти на фенолни киселини в експериментални фармакологични проучвания
(2016)[EN] This dissertation studies the psychopharmacological effects of the phenolic acids chromogenic, frolic and gallic and the flavonoid quercetin applied at an equal relatively low dose to young/healthy rats. The effects ... -
Pharmacological study of Aronia melanocarpa fruit juice // Фармакологично проучване на плодов сок от Aronia melanocarpa
(2005)[EN] A pharmacological study of Aronia melanocarpa fruit juice main effects (antioxidant, hepatoprotective, ulceroprotective, antihyperlipidemic, anti-inflammatory, antibacterial and antiviral) was carried out in experimental ... -
PSYCHOPHARMACOLOGICAL AND ORGAN PROTECTIVE EFFECTS OF ARONIA MELANOCARPA FRUIT JUICE IN EXPERIMENTAL PHARMACOLOGICAL STUDIES // ПСИХОФАРМАКОЛОГИЧНИ И ОРГАНОПРОТЕКТИВНИ ЕФЕКТИ НА ПЛОДОВ СОК ОТ ARONIA MELANOCARPA В ЕКСПЕРИМЕНТАЛНИ ФАРМАКОЛОГИЧНИ ПРОУЧВАНИЯ
(2014)[EN] The present dissertation shows that Aronia melanocarpa fruit juice is extremely rich in polyphenolic substances (proanthocyanidins, flavonoids and phenolic acids). It possesses a very high antioxidant activity against ... -
Pharmacological research of the effect of Aronia melanocarpa fruit juice in behavioral models in rats//Фармакологично проучване на ефекта на плодов сок от Aronia melanocarpa в поведенчески модели при плъхове
(2015)[EN] The dissertation represents an extensive scientific research on the psycho-pharmacological effects of Aronia melanocarpa fruit juice in young/ healthy rats and in experimental models of anxiety-depressive disorders ...
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