Browsing Катедра по пропедевтика на вътрешните болести / Department of Propaedeutics of Internal Diseases by Title
Now showing items 1-13 of 13
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Analysis of Urinary Markers for Early Renal Impairment and Their Predictive Value in Patients with Thalassemia Major // Анализ на уринни маркери за ранна бъбречна увреда и тяхната предиктивна стойност при болни с Таласемия Майор
(2019)We have examined the renal pathology in patients with β-Thalassemia Major (β-TM), and in particular the pathophysiological mechanisms for the occurrence of tubulopathies and the role of new urinary markers in their diagnosis. ... -
Biological Markers of Necrosis and Necropsy in Cardiovascular Diseases /// Биологични маркери за некроза и некроптоза при сърдечно-съдови заболявания
(2017)[EN] The prevalence of acute and chronic ischemic heart disease and heart failure is as high as 8% in Western countries. These conditions account for more than one-third of all human mortality and remain the leading causes ... -
Determinants of Quality of Life in Patients with Nonradiographic Axial Spondyloarthritis: Analysis Based on the Main Aspects of the Disease // Детерминанти на качеството на живот при пациенти с нерентгенографски аксиален спондилоартрит: анализ, базиран на основните аспекти на болестта
(Medical University of Varna, 2022)The field of seronegative spondyloarthritis (SpA) has made significant progress in recent years. This is due to the possibility of early diagnosis and increasing access to modern pathogenetic treatment and imaging ... -
Expression of Beclin-1 as a Marker for Autophagy and Its Predictive and Prognostic Performance in Patients with Metastatic Colon Cancer /// Експресията на Beclin-1 като маркер за автофагия и прогностичната му и предиктивна стойност при болни с карцином на дебелото черво в метастатичен стадий
(2017)Colorectal cancer (CRC) is the third by frequency of morbidity in the oncological morbidity worldwide. About 25% of patients are diagnosed with metastases initially and up to 50% of all patients with CRC will develop ... -
Expression of some plasma and tissue biomarkers as potential predictors for response to Anti-angiogenic therapy with bevacizumab in metastatic colorectal cancer // Експресия на някои плазмени и тъканни биомаркери като потенциални предиктори за антиангиогенезна терапия с Bevacizumab при метастатичен дебелочревен карцином
(2016)[EN] Angiogenesis is a key process in each stage of the development and progression of the malignant tumors, contributing to the transformation of cancers from in situ lesions to life-threatening metastatic disease. Vascular ... -
Frequency and Clinic-Immunological Correlations of Some C1q-Snps in Patients with Rheumatoid Arthritis and Systemic Lupus Erythematosus // Честота и клинико-имунологични корелации на някои C1q-SNPs при пациенти с ревматоиден артрит и системен лупус еритематодес
(Medical University of Varna, 2022)The study aims to assess Bulgarian RA and SLE patients and healthy controls for 5 SNPs (rs665691, rs682658, rs172378, rs294179 and rs292001) in the C1q gene cluster to analyze their associations with C1q levels and some ... -
Impact of Transcatheter Aortic Valve Implantation on the Left Ventricular Remodelling /// Въздействие на транскатетърното имплантиране на аортна клапа върху ремоделирането на лявата камера
(2016)[EN] The objective of this study was monitor and analyse the impact of transcatheter aortic valve implantation (TAVI) on left ventricular remodelling process. The study included 141 patients with severe degenerative aortic ... -
Iron Homeostasis in Healthy People and Patients with Metabolic Syndrome with Main Focus on Hepcidin – Regulatory Hormone of Iron Metabolism /// Хомеостаза на желязото при здрави хора и пациенти с метаболитен синдром с основен акцент върху хепсидина-хормона регулатор на метаболизма на желязото
(2016)[EN] We live in times of unprecedented increase of diseases of civilization – overweight, diabetes, heart disease, stress, etc. Metabolic syndrome as a complex of the above mentioned diseases spreads pandemically throughout ... -
Prospective Follow-up of Patients with Beta-Thalassemia Major for Cardio-vascular Status and Cardio-vascular Pathology /// Проспективно проследяване на сърдечно-съдовия статус и сърдечно-съдовата патология при пациенти с таласемия майор
(2017)[EN] Cardiac involvement still remains a leading cause of morbidity and mortality among patients with transfusion-dependent Thalassemia Major (TM) despite recent advances in therapeutic management. Myocardial iron overload ... -
The Role of Necroptosis in Inflammatory Bowel Disease // Ролята на некроптозата при възпалителните чревни заболявания
(Medical University of Varna, 2022)Inflammatory bowel diseases are diseases that are increasing in frequency, mainly affecting young people, and their lifelong evolution leads to significant dysfunction of the gastrointestinal tract with subsequent severe ... -
Serum Expression Levels of miR-17, miR-21, miR-29a and miR-92 as Potential Biomarkers for Recurrence after Adjuvant Chemotherapy in Colon Cancer Patients //// Микрорибонуклеинови киселини miR-17, miR-21, miR-29a и miR-92 като потенциални маркери за оценка на риск от рецидив след адювантна химиотерапия при пациенти с карцином на колона
(2016)miRNAs are a class of short (18–23 nucleotides in length), endogenous, non-protein-coding RNAs that play critical roles in diverse biological processes through negative post-transcriptional regulation (10, 11). miRNAs can ... -
Study of Clinical Activity of Rheumatoid Arthritis in Patients Treated with Biological Products // Изследване на клиничната активност на ревматоидния артрит при болни, провеждащи лечение с биологични средства
(2019)Current approach to managing RA activity through tight control and treat to target strategy in the treatment of patients requires the use of secure combined assessment tools and dynamic monitoring of the response. Two ... -
Survival and prognostics of patients with heart failure and impaired left ventricular systolic and segmental function // Преживяемост и прогноза при пациенти със сърдечна недостатъчност и нарушена левокамерна систолна и сегментна функция
(2011)[EN] Thesis' aim, patients and methods: A group of 145 patients with left ventricular dysfunction and heart failure on standard outpatient treatment with baseline demographic, laboratory and instrumental parameters were ...