Катедра по вътрешни болести II / Second Department of Internal Diseases - Gastroenterology, Endocrinology, Nephrology, Haematology
Recent Submissions
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Androgen Levels in Men with Acute and Chronic Coronary Syndrome // Андрогенни нива при мъже с остър и хроничен коронарен синдром
(Medical University of Varna, 2022)The problem of androgens in men with acute (ACS) and chronic coronary syndrome (CCS) is relevant to clarify the pathogenesis and prevention of CHD. There is evidence of a beneficial effect of androgens on the cardiac muscle ... -
Screening, Diagnosis and Clinical Evaluation of Patients with Non-Alcoholic Fatty Liver Disease // Скрининг, диагностика и клинична оценка на пациентите с неалкохолна мастна чернодробна болест
(Medical University of Varna, 2022)Non-alcoholic fatty liver disease (NAFLD) is a public health problem of global importance, affecting approximately one million individuals worldwide. It is defined by the presence of hepatic steatosis in more than 5% of ... -
Adequacy of Dialysis Treatment and the Relationship with Achieved Quality of Life and Survival in Patients with Stage V Chronic Kidney Disease // Адекватност на диализното лечение и връзката с достигнато качество на живот и преживяемост при пациенти с хронично бъбречно заболяване V стадий
(Medical University of Varna, 2022)According to the European Renal Association - European Dialysis and Transplant Association, at the end of 2016, the total number of people with chronic kidney disease (CKD) stage 5 in Europe was 564,638 people, more than ... -
Assessment and Dynamic Monitoring of Hyperphosphataemia. Predictor for Bone-Mineral Disorders in Dialysis Patients // Оценка и динамично проследяване на хиперфосфатемията – предиктор за костно-минерални нарушения при диализни пациенти
(Medical University of Varna, 2022)The thesis aims to analyze the diagnostic, clinical and therapeutic aspects of bone-mineral metabolism disorders in chronic kidney disease in the course of conservative and hemodialysis treatment. To analyze new non-invasive ... -
Monitoring and Assessment of the Nutritional Status and Markers of the Inflammatory Process in Chronic Kidney Disease Patients // Проследяване и оценка на хранителния статус и маркерите за възпалителния процес при пациенти с хронично бъбречно заболяване
(Medical University of Varna, 2022)Chronic kidney disease (CKD) is a serious public health problem that can lead to end-stage renal disease, increased cardiovascular morbidity and mortality. Identifying the predisposing factors for CKD is essential, as some ... -
Analysis of the Role of Circulating Platelet-Neutrophil Complexes as Regulators of Tumour-Induced Netosis in Indolent and Aggressive Non-Hodgkin’s Lymphomas // Анализ на ролята на циркулиращите неутрофилно-тромбоцитни комплекси като регулатори на тумор-индуцираната нетоза при индолентни и агресивни Нехочкинови лимфоми
(Medical University of Varna, 2022)Non-Hodgkin’s lymphomas (NHLs) are a heterogeneous group of clonal lymphoid diseases with a wide range of clinical, biological and histopathological features. Furthermore, NHLs are pathophysiologically associated with ... -
Comparative Characteristics of Metabolic Markers in The Assessment of Bone Health in Postmenopausal Age // Сравнителна характеристика на метаболитни маркери при оценка на костното здраве в постменопаузална възраст
(Medical University of Varna, 2022)Metabolic syndrome and osteoporosis are two socially important health problems. Their worldwide distribution is constantly growing. The potential association between metabolic syndrome and osteoporosis has long been ... -
Metabolic Profile of Patients with Hormone-Inactive Adrenal Adenomas // Метаболитен профил на пациенти с хормонално-неактивни надбъбречни аденоми
(Medical University of Varna, 2021)This thesis aims to analyse the diagnostic, metabolic, biochemical and hormonal aspects of patients with hormone-reactive adrenal adenomas. We assessed some additional markers associated with metabolic syndrome, non-alcoholic ... -
Relationship Between Erythropoietin Resistance and Secondary Hyperparathyroidism in Patients Undergoing Dialysis // Връзка между еритропоетиновата резистентност и вторичния хиперпаратиреоидизъм при пациенти на диализно лечение
(Medical University of Varna, 2021)The incidence of chronic kidney disease (CKD) has been rising rapidly in recent years, and this is a serious health problem worldwide. Anaemia is a common complication of CKD, reduces the quality of life, and increases the ... -
Level of Awareness of Patients with Chronic Kidney Disease Regarding Kidney Transplantation and the Importance of Awareness in the Choice of Renal Replacement Therapy // Ниво на информираност на пациентите с хронично бъбречно заболяване по отношение на бъбречната трансплантация и значение на информираността при избора на бъбречно заместително лечение
(Medical University of Varna, 2021)More than half a million people a year in the United States alone and about two million patients worldwide reach the end-stage renal disease (ESRD). Patients with ESRD have two options to stay alive: 1. Dialysis treatment ... -
Clinical, Biological and Genetic Markers in Risk Stratification in Patients with Myelodysplastic Syndrome // Клинико-биологични и генетични маркери в рисковата стратификация при пациенти с миелодиспластичен синдром
(Medical University of Varna, 2021)Myelodysplastic syndrome (MDS) is a heterogeneous group of hematopoietic stem cell disorders characterized by ineffective hematopoiesis, cytopenia, and an increased risk of transformation into acute myeloid leukaemia ... -
Primary Myelofibrosis, Post-Erythremia Vera and Post- Essential Thrombocythemia Myelofibrosis - Impact of Inflammatory Cytokines (Interleukin 6, Interleukin 8) and Regulators of Iron Metabolism (Hepcidin) in The Pathogenesis of Anemic Syndrome // Първична, пост-еритремична, пост-тромбоцитемична миелофиброза - участието на инфламаторни цитокини (interleukin 6, interleukin 8) и регулаторите на железния метаболизъм (хепсидин) в патогенезата на анемичния синдром
(Medical University of Varna, 2021)Myelofibrosis (MF) is a clonal haematological neoplasm with heterogeneous clinical manifestation, fibrotic tissue replacement of the haematopoiesis, bone marrow failure, extramedullary haematopoiesis, excessive splenomegaly ... -
Clinical Application of Prognostic Factors and Their Integration in a Risk and Time to Treatment Assessment Scale for Treatment-Naive B-CLL Patients // Клинично приложение на прогностичните фактори и интегрирането им в скала за оценка на риска и времето до лечение, при нелекувани пациенти с В-хронична лимфоцитна левкемия
(Medical University of Varna, 2020)Chronic lymphocytic leukaemia is one of the most common leukaemias in adults characterised by an extremely variable clinical course and different outcomes. It is defined by many factors associated with complex pathogenetic ... -
Non-Invasive Assessment of Arterial Stiffness in Patients with Type 2 Diabetes Mellitus: Correlation with Some Biomarkers // Неинвазивна оценка на артериалната ригидност при пациенти с тип 2 захарен диабет – корелация с някои биомаркери
(Medical University of Varna, 2020)Macrovascular complications of type 2 diabetes mellitus (T2DM) include vascular calcification and arterial stiffness (AS). Measurement of arterial stiffness is currently of scientific interest due to its independent ... -
Clinical Evaluation of Crohn's Disease Activity / Оценка на клиничната активност на болестта на Крон
(2018)Crohn's disease is a chronic, progressive and potentially debilitating disease. Patients with CD need long-term treatment with frequent side effects, the need of surgery and hospitalizations. Aim of this thesis is to conduct ... -
Risk Factors and Precanceroses for Hepatocellular Carcinoma /// Рискови фактори и преканцерози за хепатоцелуларен карцином
(2018)This dissertation aims to identify and analyse the risk factors and precancerous status of hepatocellular carcinoma (HCC) and its early detection by monitoring the predisposed groups of patients. Hepatocellular carcinoma ... -
Diagnosis and Management of Mineral and Bone Disorders in Patients with Chronic Kidney Disease on Conservative and Dialysis Treatment /// Диагностика и лечение на минералните и костни нарушения при болни с хронични бъбречни заболявания на консервативно и диализно лечение
(2018)[EN] Purpose of the dissertation thesis is to analyse the diagnostic, clinical and therapeutic aspects of BMD-CKD in the course of conservative and haemodialysis treatment by examining the diagnostic and prognostic value ... -
Correlation between Tumor Angiogenesis, Mutation Load, Changes in the Blood Count and the Thrombogenic Risk in Patients with Essential Thrombocythaemia and Polycythaemia Vera /// Корелационна зависимост между туморната ангиогенеза, мутационния товар, промените в кръвната картина, и тромбогенния риск при пациенти с есенциална тромбоцитемия и полицитемия вера
(2018)[EN] Thrombotic events (TE) are the main disease manifestation and cause of disability in 2-4 % of patients with Polycythaemia vera (PV) and Essential thrombocythemia (ET) per year. These data define the initial thrombotic ... -
Optimization of Clinical Approach and Dietotherapy in Gluten Enteropathy /// Оптимизиране на клиничния подход и диетолечението при глутенова ентеропатия
(2018)[EN] Gluten enteropathy is one of the most common autoimmune gastrointestinal disorders. The disease is a chronic, autoimmune form of enteropathy - with the target organ of the small intestine, genetically predisposed ... -
Markers for Evaluation of the Activity and Progression of the Kidney Disease in Adult Patients with Chronic Glomerular Disorders /// Показатели за оценка на активността и прогресията на бъбречното заболяване при възрастни пациенти с хронични гломерулопатии
(2017)[EN] Proteinuria is an important marker for the diagnosis and monitoring of the activity of chronic glomerulopathies. It is associated with increased cardiovascular risk and the risk of progressive deterioration of the ...
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