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Peculiarities in the clinical approach in patients with Wilson’s disease. // Особености в клиничния подход при пациенти с болест на Wilson.
(2014)
[EN] The dissertation is dedicated to Wilson’s disease (WD) – a rare inherited autosomal recessive disease, related to a disorder of copper metabolism. Its aim is to optimize the diagnostic and therapeutic approach to this ...
Serum levels of osteoprotegerin and glucometabolic indices in subjects with newly detected glycemic abnormalities // Серумни нива на остеопротегерин и глюкометаболитни показатели при лица с новооткрити гликемични нарушения
(2013)
[EN] Up to date there are no sufficient data for osteoprotegerin (OPG) concentrations in newly diagnosed type 2 diabetic patients. Two screening programs for glycemic abnormalities among risk groups were performed. This ...
Clinical importance of microsatellite instability and promoter methylation of DNA in colorectal cancer // Клинично значение на микросателитната нестабилност и промоторното метилиране на ДНК при колоректален карцином
(2011)
[EN] The study included 189 patients with colorectal cancer (CRC), of them 98 Bulgarian and 81 German. Data regarding familial history for cancer, tumor location along the colon, histology and stage according to TNM ...
Hepatitis C Treatment in the Stage of Advanced Liver Disease // Лечение на хепатит С в стадий на напреднало чернодробно заболяване
(Varna Medical University Presds, 2015)
[EN] This guide is a summary of the scientific evidence and clinical experience gathered as a decision making basis for patients with Hepatitis C. We intend this guide to outline the near present-future treatment behavior ...
Clinical, Diagnostic, Therapeutic and Prognostic Aspects of Autoimmune Liver Diseases /// Клинико-диагностични, терапевтични и прогностични аспекти на автоимунните чернодробни болести
(2016)
[EN] This PhD thesis focuses on the autoimmune liver diseases, namely, autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), primary sclerosing cholangitis and their overlapping syndromes. Comprehensive characterization ...
Clinical Value of Endosonography in Diagnosing and Staging of Rectal Cancer /// Клинична стойност на ендосонографията при диагностиката и стадирането на ректалния карцином
(2014)
[EN] The dissertation deals with the rectal carcinoma which is a disease of great social impact. The abilities of the different methods for diagnosis and preoperative staging are analysed. The epidemiology, cancerogenesis, ...
Markers for Evaluation of the Activity and Progression of the Kidney Disease in Adult Patients with Chronic Glomerular Disorders /// Показатели за оценка на активността и прогресията на бъбречното заболяване при възрастни пациенти с хронични гломерулопатии
(2017)
[EN] Proteinuria is an important marker for the diagnosis and monitoring of the activity of chronic glomerulopathies. It is associated with increased cardiovascular risk and the risk of progressive deterioration of the ...
Diagnosis and Management of Mineral and Bone Disorders in Patients with Chronic Kidney Disease on Conservative and Dialysis Treatment /// Диагностика и лечение на минералните и костни нарушения при болни с хронични бъбречни заболявания на консервативно и диализно лечение
(2018)
[EN] Purpose of the dissertation thesis is to analyse the diagnostic, clinical and therapeutic aspects of BMD-CKD in the course of conservative and haemodialysis treatment by examining the diagnostic and prognostic value ...
Risk Factors and Precanceroses for Hepatocellular Carcinoma /// Рискови фактори и преканцерози за хепатоцелуларен карцином
(2018)
[EN] This dissertation aims to identify and analyse the risk factors and precancerous status of hepatocellular carcinoma (HCC) and its early detection by monitoring the predisposed groups of patients. Hepatocellular carcinoma ...
Clinical Evaluation of Crohn's Disease Activity / Оценка на клиничната активност на болестта на Крон
(2018)
Crohn's disease is a chronic, progressive and potentially debilitating disease. Patients with CD need long-term treatment with frequent side effects, the need of surgery and hospitalizations. Aim of this thesis is to conduct ...