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Synthesis and Biological Evaluation of SMAC-NT Peptide Conjugates with Combined Antineoplastic and Analgesic Effect // Синтез и биологична оценка на пептидни конюгати SMAC-NT с комбинирано антинеопластично и аналгетично действие
(2019)
The rapidly increasing number of patients with neoplastic diseases and the high mortality rate among them put scientists and pharmacists in a situation of need for the development of a new, adequate treatment. In search ...
Synthesis and Characterization of Bexarotene Derivatives with Potential Biological Activity // Получаване и охарактеризиране на бексаротенови производни с потенциална биологична активност
(2019)
The dissertation deals with the preparation and characterization of the newly synthesized derivatives of the synthetic retinoid bexarotene. The continued and intensive study of the role of retinoids in the complex of ...
Resumes Of Diploma Theses (2014) for Master’s Degree in Pharmaceutical Management
(2014)
13 Resumes of diploma theses for Master's degree in Pharmaceutical Management. These theses were written and defended in 2014 at the The Faculty of Public Health, Medical University of Varna. List of Titles: COMPARATIVE ...
Biodiversity and Ethnobotanical Uses of Medicinal Plants from the Northern Black Sea Coastal Wetlands /// Биоразнообразие и приложение на лекарствените растения от Северно-Черноморските влажни зони в етноботаниката
(2017)
Biodiversity studies on the medicinal plants in any given country is the first important step in carrying out resource-saving research on the conservation and rational use of this resource. Alongside this, it is the basis ...
Study of Mutations and Expression of Genes Correlated to the Appearance of Colorectal Cancer /// Проучване на мутации и експресия на гени, корелиращи с изявата на колоректален карцином
(2017)
The aim of the current study was to analyse the mutational profile of RAS oncogene correlated to the expression levels of genes related to energy metabolism, hypoxia and genomic stability, as well as the expression levels ...
FATSOLUBLE VITAMINS IN BLACK SEA AND FRESHWATER FISH//МАСТНОРАЗТВОРИМИ ВИТАМИНИ В ЧЕРНОМОРСКИ И СЛАДКОВОДНИ РИБИ
(2015)
[EN] The objectives of the work were to investigate the fat soluble vitamins (A, E and D3) content and their percentige of recommended daily intake (RDI) of ten Black Sea (bonito, bluefish, goby, garfish, grey mullet, ...
Determination of residue chlororganic contaminants in Black Sea fish // Определяне на остатъчни хлорорганични замърсители в черноморски риби
(2013)
[EN] United Nations Environment Programme (UNEP) has designated 12 chlorinated organic compounds as hazardous pollutants because of their negative impact on human health and the environment. Among them are some organochlorine ...
New Polymeric Forms of Paclitaxel. Synthesis, Characterization and Antitumor Activity /// Нови полимерни форми на паклитаксел. Синтез, охарактеризиране и антитуморна активност
(2016)
[EN] Novel water soluble polymeric forms of paclitaxel based on polyphosphoesters were developed in this dissertation work. Poly(oxyethylene Н-phosphonate) was used for the paclitaxel immobilization by covalent bond, as ...
Biological Aspects and Prognostic Criteria for Evaluation of Oocytes and Preimplantation Embryos in Patients with Low Ovarian Reserve /// Биологични аспекти и прогностични критерии за оценка на овоцити и предимплантационни ембриони при пациентки с намален овариален резерв
(2016)
[En] This PhD thesis explores the biological aspects of in vitro fertilization in patients with low ovarian reserve and the prognostic potential of the morphological characteristics of oocytes and preimplantation embryos ...
Antioxidant activity of Bulgarian medicinal plants and related biological effects // Антиоксидантна активност на български лечебни растения и свързани с нея биологични ефекти
(2013)
[EN] The dissertation thesis is the first systematic research of Bulgarian medicinal plants in terms of antioxidant potential and its related biological effects. It provides a link between ethnopharmacological data and the ...