1. Медицина / Medicine
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Genitourinary Syndrome of Menopause in Women after Surgical and Chemical (Hormonal and Chemotherapy) Castration // Генитоуринарен синдром на менопаузата при жени след хирургична и лекарствена (хормонална и химиотерапия) кастрация
(Medical University of Varna, 2022)The Genitourinary symptom in menopause is a group of symptoms which develop after and around menopause as a result of low estrogen levels and hypo and trophic changes in the genitourinary tract in women. Apart from vaginal ... -
Clinical Presentation and Risk Prevention of Developing Urinary Tract Infections in Childhood // Клинична презентация и превенция на риска за развитие на инфекции на пикочните пътища в детска възраст
(Medical University of Varna, 2022)Diagnosing and controlling UTIs at first glance seem easy, but in practice, the most controversial clinical questions remain to be solved in Primary Healthcare; this motivates us to look for the causes. The data presented ... -
Laboratory Cardiovascular Risk Assessment in Individuals with Long-Standing Type I Diabetes Mellitus – Adipokines, Osteoprotegerin, Asymmetric Dimethyl-Arginine // Лабораторна оценка на сърдечно-съдов риск при лица с дългогодишен захарен диабет тип I - адипокини, остеопротегерин и асиметричен диметил-аргинин
(Medical University of Varna, 2023)This thesis focuses on studying diabetes mellitus type 1 (T1D) as a present-day disease with socially significant implications and laboratory cardiovascular risk (CVR) assessment in providing comprehensive patient care. ... -
Comparative Analysis of Biomarkers, Empirical and Commercial Models for Prediction of the Effect of Growth Hormone Treatment in Paediatrics // Сравнителен анализ на биомаркери, емпирични и комерсиални модели за предсказване на ефекта от лечение с растежен хормон в детска възраст
(Medical University of Varna, 2022)Growth and normal development of children depends on the normal action of growth hormone (GH). The insufficient synthesis or activity of GH leads to short stature (SS). Growth hormone deficiency (GHD) is a rare disease, ... -
Bone Health in Children with Celiac Disease // Костно здраве при целиакия в детска възраст
(Medical University of Varna, 2022)In a case-control study conducted between 2018 and 2021in the Second Children's Clinic of St. Marina University Hospital -Varna, we set ourselves the goal of evaluating the indicators of bone health in children with newly ... -
Androgen Levels in Men with Acute and Chronic Coronary Syndrome // Андрогенни нива при мъже с остър и хроничен коронарен синдром
(Medical University of Varna, 2022)The problem of androgens in men with acute (ACS) and chronic coronary syndrome (CCS) is relevant to clarify the pathogenesis and prevention of CHD. There is evidence of a beneficial effect of androgens on the cardiac muscle ... -
Imaging Markers for Staging of Rectal Carcinoma and Restaging after Neoadjuvant Therapy // Образни маркери при стадиране на ректален карцином и рестадиране след неоадювантна терапия
(Medical University of Varna, 2022)Preoperative staging and follow-up of rectal carcinoma are of utmost importance in modern oncology. This thesis aims to define imaging biomarkers for tumour response and regression before and after neoadjuvant therapy. Imaging ... -
Pharmacological Study of the Behavioral Effects of Biologically Active Substances of Plant Origin in Experimental Animal Models of Depression // Фармакологично проучване на поведенчески ефекти на биологично активни вещества от растителен произход в модели на депресия при опитни животни
(Medical University of Varna, 2022)The thesis studies the effects of Aronia melanocarpa fruit juice and the phenolic acids – chlorogenic, ferulic and gallic in experimental models of behavioural disorders in rats induced by ovariectomy and olfactory bulbectomy. ... -
The Role of Transcription Factor Zbtb20 in the Development of Interneurons in the Neocortex of Mice // Роля на транскрипционен фактор Zbtb20 в развитието на интерневрони в крайномозъчна кора на мишка
(Medical University of Varna, 2023)Interneurons are nerve cells that use gamma-aminobutyric acid (GABA) as a neurotransmitter. They arise embryonically from a germinal zone in the telencephalon called the subpallium. From there, they migrate tangentially ... -
Screening, Diagnosis and Clinical Evaluation of Patients with Non-Alcoholic Fatty Liver Disease // Скрининг, диагностика и клинична оценка на пациентите с неалкохолна мастна чернодробна болест
(Medical University of Varna, 2022)Non-alcoholic fatty liver disease (NAFLD) is a public health problem of global importance, affecting approximately one million individuals worldwide. It is defined by the presence of hepatic steatosis in more than 5% of ... -
Intraoperative and Postoperative Analgesia with TAP-Block in Patients with Lower Midline Laparotomy // Интраоперативно и постоперативно обезболяване с TAP-block при пациенти с долна срединна лапаротомия
(Medical University of Varna, 2022)Effective pain control in the perioperative period is an essential factor in the overall success of surgical treatment and patient satisfaction. Because of that, analgesia is a major part of the healing process, and regional ... -
Features of Haemodynamic Control During General Anesthesia for Laparoscopic Adrenalectomy // Особености на хемодинамичния контрол при провеждане на обща анестезия за лапароскопска адреналектомия
(Medical University of Varna, 2022)Adrenal gland tumours are found relatively often on imaging studies of the abdominal cavity on other occasions. A small percentage are hormonally active, considered rare diseases, creating specific challenges for the ... -
Enhanced Recovery after Surgery (ERAS – Enhanced Recovery After Surgery Protocol) In Gynecologic Surgery // Ускорено възстановяване след оперативно лечение (ERAS - Enhanced Recovery After Surgery протокол) в гинекологичната хирургия
(Medical University of Varna, 2022)Enhanced Recovery After Surgery (ERAS) program is a complex system of procedures requiring a multidisciplinary team of trained experts, including nurses, anesthesiologists, gynaecologists, and psychologists, who engage in ... -
Procalcitonin and Delta Neutrophil Index Levels in the Surgery of Head and Neck Inflammatory Diseases // Стойности на прокалцитонина и делта неутрофилния индекс в хирургията на възпалителните заболяванията на главата и шията
(Medical University of Varna, 2022)The range of diseases in the head and neck area is large, and their diagnosis is often challenging for the maxillofacial surgeon. Inflammatory diseases of the face and neck, as the most visible and representative parts of ... -
Long-Term Analysis of Joint Changes in Patients with Documented and Treated Meniscal Injuries // Дългосрочен анализ на ставни изменения при пациенти с документирани и лекувани менискални увреди
(Medical University of Varna, 2022)Meniscal injuries are often accompanied by damage to the articular cartilage. Arthroscopic partial meniscectomy (APM) is the primary method of surgical treatment. After removing a significant amount of meniscal tissue, the ... -
Innovative Breast Phantoms for Studying Image Quality in Modern Mammographic Techniques // Иновативни фантоми за изследване качеството на изображението при съвременни мамографски техники
(Medical University of Varna, 2022)This doctoral thesis aims to create, validate, and use innovative computational phantoms to study the image quality of modern mammographic techniques, such as tomosynthesis and contrast-enhanced mammography (CEM), which ... -
Investigation of Bacteraemia and Invasive Fungal Infections in Patients Following Autologous and Allogeneic Hematopoietic Stem Cell Transplantation // Проучване върху бактериемиите и инвазивните микотични инфекции при пациенти след автоложна и алогенна хематопоетична стволово-клетъчна трансплантация
(Medical University of Varna, 2022)The study aimed to conduct a clinical-microbiological investigation on bacteraemia and invasive mycotic infections in patients after autologous and allogeneic hematopoietic stem cell transplantation, carried out in the ... -
Genetic Diagnostic Study among Pediatric Patients with Hereditary Pathology Who Received Genetic Counselling // Генетико-диагностично проучване при лица в детска възраст с наследствена патология, преминали през кабинета за генетично консултиране
(Medical University of Varna, 2022)Hereditary diseases and congenital anomalies are associated with serious adverse consequences for paediatric patients, their families, the health systems, and society. Medical-genetic counselling is essential in the ... -
Diagnostic Approaches and Clinical Management in Hydronephrosis during Pregnancy // Диагностични подходи и клинично поведение при хидронефроза по време на бременност
(Medical University of Varna, 2022)Drainage disorders of the urinary tract often lead to complications during pregnancy. Until now, no definitive standpoint/guideline indicates the management of a pregnant woman with symptomatic hydronephrosis. This leads ... -
Pharmacological Investigation of the Effects of Aronia Melanocarpa Fruit Juice in an Experimental Model of Metabolic Syndrome // Фармакологично проучване на ефектите на плодов сок от Aronia melanocarpa в експериментален модел на метаболитен синдром
(Medical University of Varna, 2022)This thesis aims to study and summarize the pharmacological effects of Aronia melanocarpa fruit juice in rats with diet-induced metabolic syndrome. For this objective, male Wistar rats were fed a high-fat, high-fructose ...
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